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Rat Nr2c2 cDNA Clone(NM_017323.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR011038

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Gene Information

Cat. No. CDFR011038
Description NativeORF clone of Rattus norvegicus nuclear receptor subfamily 2, group C, member 2 (Nr2c2) as transfection-ready DNA NM_017323.1
Product Type cDAN Clone
Gene Abbr Nr2c2
Species Rat
Vector pCMV6Entry
Target Gene NR2C2
Background This gene encodes a protein that belongs to the nuclear hormone receptor family. Members of this family act as ligand-activated transcription factors and function in many biological processes such as development, cellular differentiation and homeostasis. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. The protein encoded by this gene plays a role in protecting cells from oxidative stress and damage induced by ionizing radiation. The lack of a similar gene in mouse results in growth retardation, severe spinal curvature, subfertility, premature aging, and prostatic intraepithelial neoplasia (PIN) development. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]
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