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Rat Nlrp1a cDNA Clone(NM_001145755.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR010347

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Gene Information

Cat. No. CDFR010347
Description NativeORF clone of Rattus norvegicus NLR family, pyrin domain containing 1 (Nlrp1) as transfection-ready DNA NM_001145755.1
Product Type cDAN Clone
Gene Abbr Nlrp1a
Species Rat
Vector pCMV6Entry
Target Gene Nlrp1a
Background Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and nucleic acid binding activity. Involved in positive regulation of interleukin-1 beta production and response to muramyl dipeptide. Acts upstream of or within defense response to bacterium and programmed necrotic cell death. Predicted to be located in nucleoplasm. Predicted to be part of NLRP1 inflammasome complex and NLRP3 inflammasome complex. Predicted to be active in cytosol and nucleus. Human ortholog(s) of this gene implicated in vitiligo. Orthologous to human NLRP1 (NLR family pyrin domain containing 1). [provided by Alliance of Genome Resources, Feb 2025]
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