Rat Nhp2 cDNA Clone(NM_001105779.1)

Name: Rat Nhp2 cDNA Clone(NM_001105779.1)
SKU: CDFR005513
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR005513

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Product Information

Gene Information

Cat. No.	CDFR005513
Description	NativeORF clone of Rattus norvegicus nucleolar protein family A, member 2 (Nola2) as transfection-ready DNA NM_001105779.1
Product Type	cDAN Clone
Gene Abbr	Nhp2
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

NHP2

Background

This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nhp2p. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008]

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