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Rat Nfu1 cDNA Clone(NM_001106606.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR006361

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Gene Information

Cat. No. CDFR006361
Description NativeORF clone of Rattus norvegicus NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae) (Nfu1) as transfection-ready DNA NM_001106606.2
Product Type cDAN Clone
Gene Abbr Nfu1
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene NFU1
Background This gene encodes a protein that is localized to mitochondria and plays a critical role in iron-sulfur cluster biogenesis. The encoded protein assembles and transfers 4Fe-4S clusters to target apoproteins including succinate dehydrogenase and lipoic acid synthase. Mutations in this gene are a cause of multiple mitochondrial dysfunctions syndrome-1, and pseudogenes of this gene are located on the short arms of chromosomes 1 and 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
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