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Rat Nfkbia cDNA Clone(NM_001105720.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR005311

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Gene Information

Cat. No. CDFR005311
Description NativeORF clone of Rattus norvegicus nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (Nfkbia) as transfection-ready DNA NM_001105720.2
Product Type cDAN Clone
Gene Abbr Nfkbia
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene NFKBIA
Background This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]
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