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Rat Neu1 cDNA Clone(NM_031522.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR012682

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Gene Information

Cat. No. CDFR012682
Description NativeORF clone of Rattus norvegicus sialidase 1 (lysosomal sialidase) (Neu1) as transfection-ready DNA NM_031522.3
Product Type cDAN Clone
Gene Abbr Neu1
Species Rat
Vector pCMV6Entry
Target Gene NEU1
Background The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity. [provided by RefSeq, Jul 2008]
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