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Rat Ndrg1 ORF Clone(NM_001011991.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR369508

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Gene Information

Cat. No. CDCR369508
Product Type ORF Clone
Gene Abbr Ndrg1
Species Rat
Tag C-terminal Myc-DDK
ORF Size 1185 bp
Vector pCMV6-Entry
Target Gene NDRG1
Background This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
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