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Rat Nae1 cDNA Clone(NM_032072.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR012423

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Gene Information

Cat. No. CDFR012423
Description NativeORF clone of Rattus norvegicus NEDD8 activating enzyme E1 subunit 1 (Nae1) as transfection-ready DNA NM_032072.2
Product Type cDAN Clone
Gene Abbr Nae1
Species Rat
Vector pCMV6Entry
Target Gene NAE1
Background The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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