Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDCH391737
| Cat. No. | CDCH391737 |
| Product Type | ORF clone |
| Gene Abbr | NFASC |
| Species | Rat |
| Host Cell | Bacterial |
| Source | Bacterial |
| ORF Size | 9825bp |
| Size | 1ug |
| Format | Clear Liquid |
| Vector | pORF |
| Buffer | 10mM Tris-HCI, 1mM EDTA, pH8.0 |
| Warning | pORF-rNfasc ORF Vector is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. |
| Storage | 1 year when stored at -20°C or lower in a non-frost free freezer. |
| Target Gene | NFASC |
| Background | This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.[provided by RefSeq, May 2009] |
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