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Rat Mycbp2 ORF Clone(NM_001106055.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR372857

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Product Information

Gene Information

Cat. No. CDCR372857
Product Type ORF Clone
Gene Abbr Mycbp2
Species Rat
Tag C-terminal Myc-DDK
ORF Size 14250 bp
Vector pCMV6-Entry
Target Gene MYCBP2
Background This gene encodes an E3 ubiquitin-protein ligase and member of the PHR (Phr1/MYCBP2, highwire and RPM-1) family of proteins. The encoded protein plays a role in axon guidance and synapse formation in the developing nervous system. In mammalian cells, this protein regulates the cAMP and mTOR signaling pathways, and may additionally regulate autophagy. Reduced expression of this gene has been observed in acute lymphoblastic leukemia patients and a mutation in this gene has been identified in patients with a rare inherited vision defect. [provided by RefSeq, Mar 2017]
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