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Rat Mxd1 cDNA Clone(NM_001100749.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR005347

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Gene Information

Cat. No. CDFR005347
Description NativeORF clone of Rattus norvegicus max dimerization protein 1 (Mxd1) as transfection-ready DNA NM_001100749.1
Product Type cDAN Clone
Gene Abbr Mxd1
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene MXD1
Background This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]
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