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Rat Mtpn cDNA Clone(NM_024374.4)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR012318

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Gene Information

Cat. No. CDFR012318
Description NativeORF clone of Rattus norvegicus myotrophin (Mtpn) as transfection-ready DNA NM_024374.4
Product Type cDAN Clone
Gene Abbr Mtpn
Species Rat
Vector pCMV6Entry
Target Gene MTPN
Background The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3' end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen that is associated with myeloproliferative disease. [provided by RefSeq, Jul 2008]
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