Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR010264
| Cat. No. | CDFR010264 |
| Description | NativeORF clone of Rattus norvegicus metallothionein 2A (Mt2A) as transfection-ready DNA NM_001137564.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Mt2A |
| Species | Rat |
| Vector | pCMV6Entry |
| Target Gene | MT2A |
| Background | This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, are cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions, altering the intracellular concentration of heavy metals in the cell. These proteins act as anti-oxidants, protect against hydroxyl free radicals, are important in homeostatic control of metal in the cell, and play a role in detoxification of heavy metals. The encoded protein interacts with the protein encoded by the homeobox containing 1 gene in some cell types, controlling intracellular zinc levels, affecting apoptotic and autophagy pathways. Some polymorphisms in this gene are associated with an increased risk of cancer. [provided by RefSeq, Sep 2017] |
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