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Rat Mt2A cDNA Clone(NM_001137564.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR010264

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Gene Information

Cat. No. CDFR010264
Description NativeORF clone of Rattus norvegicus metallothionein 2A (Mt2A) as transfection-ready DNA NM_001137564.1
Product Type cDAN Clone
Gene Abbr Mt2A
Species Rat
Vector pCMV6Entry
Target Gene MT2A
Background This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, are cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions, altering the intracellular concentration of heavy metals in the cell. These proteins act as anti-oxidants, protect against hydroxyl free radicals, are important in homeostatic control of metal in the cell, and play a role in detoxification of heavy metals. The encoded protein interacts with the protein encoded by the homeobox containing 1 gene in some cell types, controlling intracellular zinc levels, affecting apoptotic and autophagy pathways. Some polymorphisms in this gene are associated with an increased risk of cancer. [provided by RefSeq, Sep 2017]
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