Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR014256
| Cat. No. | CDFR014256 |
| Description | NativeORF clone of Rattus norvegicus metallothionein 1a (Mt1a) as transfection-ready DNA NM_138826.4 |
| Product Type | cDAN Clone |
| Gene Abbr | Mt1a |
| Species | Rat |
| Vector | pCMV6Entry |
| Target Gene | MT1A |
| Background | This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, are cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions. The conserved cysteine residues co-ordinate metal ions using mercaptide linkages. These proteins act as anti-oxidants, protect against hydroxyl free radicals, are important in homeostatic control of metal in the cell, and play a role in detoxification of heavy metals. Disruption of two metallothionein genes in mouse resulted in defects in protection against heavy metals, oxidative stress, immune reactions, carcinogens, and displayed obesity. [provided by RefSeq, Sep 2017] |
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