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Rat Mt1a cDNA Clone(NM_138826.4)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR014256

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Gene Information

Cat. No. CDFR014256
Description NativeORF clone of Rattus norvegicus metallothionein 1a (Mt1a) as transfection-ready DNA NM_138826.4
Product Type cDAN Clone
Gene Abbr Mt1a
Species Rat
Vector pCMV6Entry
Target Gene MT1A
Background This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, are cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions. The conserved cysteine residues co-ordinate metal ions using mercaptide linkages. These proteins act as anti-oxidants, protect against hydroxyl free radicals, are important in homeostatic control of metal in the cell, and play a role in detoxification of heavy metals. Disruption of two metallothionein genes in mouse resulted in defects in protection against heavy metals, oxidative stress, immune reactions, carcinogens, and displayed obesity. [provided by RefSeq, Sep 2017]
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