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Rat Msl3 cDNA Clone(NM_001014111.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR003242

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Gene Information

Cat. No. CDFR003242
Description NativeORF clone of Rattus norvegicus male-specific lethal 3-like 1 (Drosophila) (Msl3l1) as transfection-ready DNA NM_001014111.1
Product Type cDAN Clone
Gene Abbr Msl3
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene MSL3
Background This gene encodes a nuclear protein that is similar to the product of the Drosophila male-specific lethal-3 gene. The Drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus, the human protein is thought to play a similar function in chromatin remodeling and transcriptional regulation, and it has been found as part of a complex that is responsible for histone H4 lysine-16 acetylation. This gene can undergo X inactivation. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 7 and 8. [provided by RefSeq, Jul 2010]
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