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Rat Mrps11 cDNA Clone(NM_001109148.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR008694

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Gene Information

Cat. No. CDFR008694
Description NativeORF clone of Rattus norvegicus mitochondrial ribosomal protein S11 (Mrps11), nuclear gene encoding mitochondrial protein as transfection-ready DNA NM_001109148.1
Product Type cDAN Clone
Gene Abbr Mrps11
Species Rat
Vector pCMV6Entry
Target Gene MRPS11
Background Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that contains a high level of sequence similarity with ribosomal protein S11P family members. A pseudogene corresponding to this gene is found on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2016]
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