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Rat Mrpl47 cDNA Clone(NM_001037183.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR003907

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Gene Information

Cat. No. CDFR003907
Description NativeORF clone of Rattus norvegicus mitochondrial ribosomal protein L47 (Mrpl47), nuclear gene encoding mitochondrial protein as transfection-ready DNA NM_001037183.1
Product Type cDAN Clone
Gene Abbr Mrpl47
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene MRPL47
Background Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene is immediately adjacent to the gene for BAF complex 53 kDa subunit protein a (BAF53a), in a tail-to-tail orientation. Two transcript variants encoding different protein isoforms have been identified. [provided by RefSeq, Jul 2008]
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