Rat Mrpl45 cDNA Clone(NM_001105834.1)

Name: Rat Mrpl45 cDNA Clone(NM_001105834.1)
SKU: CDFR005565
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR005565

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Product Information

Gene Information

Cat. No.	CDFR005565
Description	NativeORF clone of Rattus norvegicus mitochondrial ribosomal protein L45 (Mrpl45), nuclear gene encoding mitochondrial protein as transfection-ready DNA NM_001105834.1
Product Type	cDAN Clone
Gene Abbr	Mrpl45
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

MRPL45

Background

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 2p and 17q. [provided by RefSeq, May 2013]

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