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Rat Mrpl42 cDNA Clone(NM_001106782.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR006511

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Gene Information

Cat. No. CDFR006511
Description NativeORF clone of Rattus norvegicus mitochondrial ribosomal protein L42 (Mrpl42), nuclear gene encoding mitochondrial protein as transfection-ready DNA NM_001106782.1
Product Type cDAN Clone
Gene Abbr Mrpl42
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene MRPL42
Background Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a protein identified as belonging to both the 28S and the 39S subunits. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 4q, 6p, 6q, 7p, and 15q. [provided by RefSeq, May 2011]
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