Rat Mrpl40 cDNA Clone(NM_001024865.1)

Name: Rat Mrpl40 cDNA Clone(NM_001024865.1)
SKU: CDFR003697
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR003697

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Product Information

Gene Information

Cat. No.	CDFR003697
Description	NativeORF clone of Rattus norvegicus mitochondrial ribosomal protein L40 (Mrpl40), nuclear gene encoding mitochondrial protein as transfection-ready DNA NM_001024865.1
Product Type	cDAN Clone
Gene Abbr	Mrpl40
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

MRPL40

Background

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome. [provided by RefSeq, Jul 2008]

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