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Rat Mri1 cDNA Clone(NM_001010947.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR002294

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Gene Information

Cat. No. CDFR002294
Description NativeORF clone of Rattus norvegicus translation initiation factor eIF-2B subunit alpha/beta/delta-like protein (RGD1307789) as transfection-ready DNA NM_001010947.1
Product Type cDAN Clone
Gene Abbr Mri1
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene MRI1
Background This enzyme functions in the methionine salvage pathway by catalyzing the interconversion of methylthioribose-1-phosphate and methythioribulose-1-phosphate. Elevated expression of the encoded protein is associated with metastatic melanoma and this protein promotes melanoma cell invasion independent of its enzymatic activity. Mutations in this gene may be associated with vanishing white matter disease (VMWD). [provided by RefSeq, Jul 2016]
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