Pages
Products

Rat Mpzl2 cDNA Clone(NM_001106818.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR006544

Inquire for Price

Product Information

Gene Information

Cat. No. CDFR006544
Description NativeORF clone of Rattus norvegicus myelin protein zero-like 2 (Mpzl2) as transfection-ready DNA NM_001106818.1
Product Type cDAN Clone
Gene Abbr Mpzl2
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene MPZL2
Background Thymus development depends on a complex series of interactions between thymocytes and the stromal component of the organ. Epithelial V-like antigen (EVA) is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression. This gene is expressed in the thymus and in several epithelial structures early in embryogenesis. It is highly homologous to the myelin protein zero and, in thymus-derived epithelial cell lines, is poorly soluble in nonionic detergents, strongly suggesting an association to the cytoskeleton. Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenesis. The protein bears a characteristic V-type domain and two potential N-glycosylation sites in the extracellular domain; a putative serine phosphorylation site for casein kinase 2 is also present in the cytoplasmic tail. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Quick Inquiry

Q & A

Customer Reviews

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Needs improvement

Satisfaction

General satisfaction

Very satisfaction