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Rat Mms22l cDNA Clone(NM_001135780.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR009808

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Gene Information

Cat. No. CDFR009808
Description NativeORF clone of Rattus norvegicus similar to CG14803-PA (RGD1304693) as transfection-ready DNA NM_001135780.1
Product Type cDAN Clone
Gene Abbr Mms22l
Species Rat
Vector pCMV6Entry
Target Gene MMS22L
Background The protein encoded by this gene forms a complex with tonsoku-like, DNA repair protein (TONSL), and this complex recognizes and repairs DNA double-strand breaks at sites of stalled or collapsed replication forks. The encoded protein also can bind with the histone-associated protein NFKBIL2 to help regulate the chromatin state at stalled replication forks. Finally, this gene appears to be overexpressed in most lung and esophageal cancers. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2017]
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