Rat Mmp14 cDNA Clone(NM_031056.1)

Name: Rat Mmp14 cDNA Clone(NM_031056.1)
SKU: CDFR012532
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR012532

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Product Information

Gene Information

Cat. No.	CDFR012532
Description	NativeORF clone of Rattus norvegicus matrix metallopeptidase 14 (membrane-inserted) (Mmp14) as transfection-ready DNA NM_031056.1
Product Type	cDAN Clone
Gene Abbr	Mmp14
Species	Rat
Vector	pCMV6Entry

Target Gene

MMP14

Background

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq, Jul 2008]

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