Rat Mmp13 cDNA Clone(NM_133530.1)

Name: Rat Mmp13 cDNA Clone(NM_133530.1)
SKU: CDFR014049
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR014049

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Product Information

Gene Information

Cat. No.	CDFR014049
Description	NativeORF clone of Rattus norvegicus matrix metallopeptidase 13 (Mmp13) as transfection-ready DNA NM_133530.1
Product Type	cDAN Clone
Gene Abbr	Mmp13
Species	Rat
Vector	pCMV6Entry

Target Gene

MMP13

Background

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016]

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