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Rat Mmadhc cDNA Clone(NM_001004280.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR001427

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Gene Information

Cat. No. CDFR001427
Description NativeORF clone of Rattus norvegicus similar to RIKEN cDNA 2010311D03 (RGD1303272) as transfection-ready DNA NM_001004280.1
Product Type cDAN Clone
Gene Abbr Mmadhc
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene MMADHC
Background This gene encodes a mitochondrial protein that is involved in an early step of vitamin B12 metabolism. Vitamin B12 (cobalamin) is essential for normal development and survival in humans. Mutations in this gene cause methylmalonic aciduria and homocystinuria type cblD (MMADHC), a disorder of cobalamin metabolism that is characterized by decreased levels of the coenzymes adenosylcobalamin and methylcobalamin. Pseudogenes have been identified on chromosomes 11 and X.[provided by RefSeq, Nov 2008]
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