Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR002562
| Cat. No. | CDFR002562 |
| Description | NativeORF clone of Rattus norvegicus melanophilin (Mlph) as transfection-ready DNA NM_001012135.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Mlph |
| Species | Rat |
| Size | 10 ug |
| Vector | pCMV6Entry |
| Target Gene | MLPH |
| Background | This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013] |
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