Rat Mdh1 cDNA Clone(NM_033235.1)

Name: Rat Mdh1 cDNA Clone(NM_033235.1)
SKU: CDFR013009
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR013009

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Product Information

Gene Information

Cat. No.	CDFR013009
Description	NativeORF clone of Rattus norvegicus malate dehydrogenase 1, NAD (soluble) (Mdh1) as transfection-ready DNA NM_033235.1
Product Type	cDAN Clone
Gene Abbr	Mdh1
Species	Rat
Vector	pCMV6Entry

Target Gene

MDH1

Background

This gene encodes an enzyme that catalyzes the NAD/NADH-dependent, reversible oxidation of malate to oxaloacetate in many metabolic pathways, including the citric acid cycle. Two main isozymes are known to exist in eukaryotic cells: one is found in the mitochondrial matrix and the other in the cytoplasm. This gene encodes the cytosolic isozyme, which plays a key role in the malate-aspartate shuttle that allows malate to pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes. Alternatively spliced transcript variants have been found for this gene. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Pseudogenes have been identified on chromosomes X and 6. [provided by RefSeq, Feb 2016]

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