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Rat Mcm2 cDNA Clone(NM_001107873.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR007521

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Gene Information

Cat. No. CDFR007521
Description NativeORF clone of Rattus norvegicus minichromosome maintenance complex component 2 (Mcm2) as transfection-ready DNA NM_001107873.2
Product Type cDAN Clone
Gene Abbr Mcm2
Species Rat
Vector pCMV6Entry
Target Gene MCM2
Background The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012]
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