Rat Mcm10 cDNA Clone(NM_001107366.1)

Name: Rat Mcm10 cDNA Clone(NM_001107366.1)
SKU: CDFR007067
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR007067

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Product Information

Gene Information

Cat. No.	CDFR007067
Description	NativeORF clone of Rattus norvegicus minichromosome maintenance complex component 10 (Mcm10) as transfection-ready DNA NM_001107366.1
Product Type	cDAN Clone
Gene Abbr	Mcm10
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

MCM10

Background

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]

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