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Rat Mccc2 ORF Clone(NM_001012177.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR369690

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Gene Information

Cat. No. CDCR369690
Gene Abbr Mccc2
Species Rat
Tag C-terminal Myc-DDK
Vector pCMV6-Entry
Target Gene MCCC2
Background This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2018]
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