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Rat Mbd3 cDNA Clone(NM_001108735.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR008323

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Gene Information

Cat. No. CDFR008323
Description NativeORF clone of Rattus norvegicus methyl-CpG binding domain protein 3 (Mbd3) as transfection-ready DNA NM_001108735.1
Product Type cDAN Clone
Gene Abbr Mbd3
Species Rat
Vector pCMV6Entry
Target Gene MBD3
Background DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. This gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD). The encoded protein is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
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