Rat Mbd1 cDNA Clone(NM_001011924.1)

Name: Rat Mbd1 cDNA Clone(NM_001011924.1)
SKU: CDFR002354
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR002354

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Product Information

Gene Information

Cat. No.	CDFR002354
Description	NativeORF clone of Rattus norvegicus methyl-CpG binding domain protein 1 (Mbd1) as transfection-ready DNA NM_001011924.1
Product Type	cDAN Clone
Gene Abbr	Mbd1
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

MBD1

Background

The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains multiple domains: MBD at the N-terminus that functions both in binding to methylated DNA and in protein interactions; several CXXC-type zinc finger domains that mediate binding to non-methylated CpG dinucleotides; transcriptional repression domain (TRD) at the C-terminus that is involved in transcription repression and in protein interactions. Numerous alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Feb 2011]

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