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Rat Max cDNA Clone(NM_022210.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR011895

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Gene Information

Cat. No. CDFR011895
Description NativeORF clone of Rattus norvegicus MYC associated factor X (Max) as transfection-ready DNA NM_022210.1
Product Type cDAN Clone
Gene Abbr Max
Species Rat
Vector pCMV6Entry
Target Gene MAX
Background The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
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