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Rat Map3k7 cDNA Clone(NM_001107920.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR007565

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Gene Information

Cat. No. CDFR007565
Description NativeORF clone of Rattus norvegicus mitogen activated protein kinase kinase kinase 7 (Map3k7) as transfection-ready DNA NM_001107920.2
Product Type cDAN Clone
Gene Abbr Map3k7
Species Rat
Vector pCMV6Entry
Target Gene MAP3K7
Background The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
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