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Rat Lzts1 cDNA Clone(NM_153470.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR014604

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Gene Information

Cat. No. CDFR014604
Description NativeORF clone of Rattus norvegicus leucine zipper, putative tumor suppressor 1 (Lzts1) as transfection-ready DNA NM_153470.1
Product Type cDAN Clone
Gene Abbr Lzts1
Species Rat
Vector pCMV6Entry
Target Gene LZTS1
Background This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer. [provided by RefSeq, Nov 2009]
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