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Rat Lta cDNA Clone(NM_080769.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR013832

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Gene Information

Cat. No. CDFR013832
Description NativeORF clone of Rattus norvegicus lymphotoxin alpha (TNF superfamily, member 1) (Lta) as transfection-ready DNA NM_080769.2
Product Type cDAN Clone
Gene Abbr Lta
Species Rat
Vector pCMV6Entry
Target Gene LTA
Background The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]
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