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Rat Lpin3 cDNA Clone(NM_001014184.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR003299

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Gene Information

Cat. No. CDFR003299
Description NativeORF clone of Rattus norvegicus lipin 3 (Lpin3) as transfection-ready DNA NM_001014184.1
Product Type cDAN Clone
Gene Abbr Lpin3
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene LPIN3
Background The protein encoded by this gene is a member of the lipin family of proteins, and all family members share strong homology in their C-terminal region. This protein is thought to form hetero-oligomers with other lipin family members, while one family member, lipin 1, can also form homo-oligomers. This protein contains conserved motifs for phosphatidate phosphatase 1 (PAP1) activity as well as a domain that interacts with a transcriptional co-activator. Lipin complexes act in the cytoplasm to catalyze the dephosphorylation of phosphatidic acid to produce diacylglycerol, which is the precursor of both triglycerides and phospholipids. Lipin complexes are also thought to regulate gene expression as transcriptional co-activators in the nucleus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]
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