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Rat Lonp2 cDNA Clone(NM_001033689.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR004247

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Gene Information

Cat. No. CDFR004247
Description NativeORF clone of Rattus norvegicus lon peptidase 2, peroxisomal (Lonp2) as transfection-ready DNA NM_001033689.1
Product Type cDAN Clone
Gene Abbr Lonp2
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene LONP2
Background In human, peroxisomes function primarily to catalyze fatty acid beta-oxidation and, as a by-product, produce hydrogen peroxide and superoxide. The protein encoded by this gene is an ATP-dependent protease that likely plays a role in maintaining overall peroxisome homeostasis as well as proteolytically degrading peroxisomal proteins damaged by oxidation. The protein has an N-terminal Lon N substrate recognition domain, an ATPase domain, a proteolytic domain, and, in some isoforms, a C-terminal peroxisome targeting sequence. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2017]
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