Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR010343
| Cat. No. | CDFR010343 |
| Description | NativeORF clone of Rattus norvegicus LIM and senescent cell antigen-like domains 1 (Lims1) as transfection-ready DNA NM_001145456.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Lims1 |
| Species | Rat |
| Vector | pCMV6Entry |
| Target Gene | LIMS1 |
| Background | The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010] |
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