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Rat Lims1 cDNA Clone(NM_001145456.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR010343

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Gene Information

Cat. No. CDFR010343
Description NativeORF clone of Rattus norvegicus LIM and senescent cell antigen-like domains 1 (Lims1) as transfection-ready DNA NM_001145456.1
Product Type cDAN Clone
Gene Abbr Lims1
Species Rat
Vector pCMV6Entry
Target Gene LIMS1
Background The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
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