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Rat Lcp1 cDNA Clone(NM_001012044.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR002472

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Gene Information

Cat. No. CDFR002472
Description NativeORF clone of Rattus norvegicus lymphocyte cytosolic protein 1 (Lcp1) as transfection-ready DNA NM_001012044.1
Product Type cDAN Clone
Gene Abbr Lcp1
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene LCP1
Background Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. [provided by RefSeq, Jul 2008]
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