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Rat Lat ORF Clone(NM_030853.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR379422

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Product Information

Gene Information

Cat. No. CDCR379422
Product Type ORF Clone
Gene Abbr Lat
Species Rat
Tag C-terminal Myc-DDK
ORF Size 726 bp
Vector pCMV6-Entry
Target Gene LAT
Background The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
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