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Rat L2hgdh cDNA Clone(NM_001108028.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR007699

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Gene Information

Cat. No. CDFR007699
Description NativeORF clone of Rattus norvegicus L-2-hydroxyglutarate dehydrogenase (L2hgdh), nuclear gene encoding mitochondrial protein as transfection-ready DNA NM_001108028.1
Product Type cDAN Clone
Gene Abbr L2hgdh
Species Rat
Vector pCMV6Entry
Target Gene L2HGDH
Background This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe cognitive disability. [provided by RefSeq, Jul 2008]
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