Rat Kpna6 cDNA Clone(NM_001015029.2)

Name: Rat Kpna6 cDNA Clone(NM_001015029.2)
SKU: CDFR003427
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR003427

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Product Information

Gene Information

Cat. No.	CDFR003427
Description	NativeORF clone of Rattus norvegicus karyopherin alpha 6 (importin alpha 7) (Kpna6) as transfection-ready DNA NM_001015029.2
Product Type	cDAN Clone
Gene Abbr	Kpna6
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

KPNA6

Background

Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family. [provided by RefSeq, Jul 2008]

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