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Rat Klhl6 cDNA Clone(NM_001105867.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR005597

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Gene Information

Cat. No. CDFR005597
Description NativeORF clone of Rattus norvegicus kelch-like 6 (Drosophila) (Klhl6) as transfection-ready DNA NM_001105867.1
Product Type cDAN Clone
Gene Abbr Klhl6
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene KLHL6
Background This gene encodes a member of the kelch-like (KLHL) family of proteins, which is involved in B-lymphocyte antigen receptor signaling and germinal-center B-cell maturation. The encoded protein contains an N-terminal broad-complex, tramtrack and bric a brac (BTB) domain that facilitates protein binding and dimerization, a BTB and C-terminal kelch (BACK) domain, and six C-terminal kelch repeat domains. Naturally occurring mutations in this gene are associated with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]
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