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Rat Kirrel3 cDNA Clone(NM_001048215.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR004965

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Gene Information

Cat. No. CDFR004965
Description NativeORF clone of Rattus norvegicus kin of IRRE like 3 (Drosophila) (Kirrel3) as transfection-ready DNA NM_001048215.1
Product Type cDAN Clone
Gene Abbr Kirrel3
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene KIRREL3
Background The protein encoded by this gene is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. The protein encoded by this gene is a synaptic cell adhesion molecule with multiple extracellular immunoglobulin-like domains and a cytoplasmic PDZ domain-binding motif. Mutations in this gene are associated with several neurological and cognitive disorders. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017]
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