Rat Kcne3 cDNA Clone(NM_022235.2)

Name: Rat Kcne3 cDNA Clone(NM_022235.2)
SKU: CDFR011919
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR011919

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Product Information

Gene Information

Cat. No.	CDFR011919
Description	NativeORF clone of Rattus norvegicus potassium voltage-gated channel, Isk-related subfamily, gene 3 (Kcne3) as transfection-ready DNA NM_022235.2
Product Type	cDAN Clone
Gene Abbr	Kcne3
Species	Rat
Vector	pCMV6Entry

Target Gene

KCNE3

Background

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the kidney. A missense mutation in this gene is associated with hypokalemic periodic paralysis. [provided by RefSeq, Jul 2008]

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