Rat Jph3 cDNA Clone(NM_001107437.1)

Name: Rat Jph3 cDNA Clone(NM_001107437.1)
SKU: CDFR007132
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR007132

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Product Information

Gene Information

Cat. No.	CDFR007132
Description	NativeORF clone of Rattus norvegicus junctophilin 3 (Jph3) as transfection-ready DNA NM_001107437.1
Product Type	cDAN Clone
Gene Abbr	Jph3
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

JPH3

Background

Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. CAG/CTG repeat expansion from normally 6-28 repeats to 40-59 repeats in the 3' UTR of this gene have been associated with Huntington disease-like 2 (HDL2). This gene is a member of the junctophilin gene family. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2016]

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