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Rat Il16 ORF Clone(NM_001105749.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR372571

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Gene Information

Cat. No. CDCR372571
Product Type ORF Clone
Gene Abbr Il16
Species Rat
Tag C-terminal Myc-DDK
ORF Size 3972 bp
Vector pCMV6-Entry
Target Gene IL16
Background The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
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