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Rat Igtp cDNA Clone(NM_001008765.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR001932

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Gene Information

Cat. No. CDFR001932
Description NativeORF clone of Rattus norvegicus interferon gamma induced GTPase (Igtp) as transfection-ready DNA NM_001008765.1
Product Type cDAN Clone
Gene Abbr Igtp
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene Igtp
Background Enables GTPase activity. Involved in several processes, including defense response to other organism; negative regulation of PERK-mediated unfolded protein response; and positive regulation of autophagosome maturation. Acts upstream of or within cellular response to interferon-beta. Located in cytosol. Is active in endoplasmic reticulum. Is expressed in alimentary system; hemolymphoid system; liver; thymus primordium; and tongue. Human ortholog(s) of this gene implicated in inflammatory bowel disease 19 and tuberculosis. Orthologous to human IRGM (immunity related GTPase M). [provided by Alliance of Genome Resources, Feb 2025]
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